STXBP3

STXBP3
Dynodwyr
Cyfenwau	STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C, Syntaxin binding protein 3
Dynodwyr allanol	OMIM: 608339 HomoloGene: 5260 GeneCards: STXBP3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • syntaxin-1 binding • GO:0001948, GO:0016582 protein binding • syntaxin binding Cydrannau o'r gell • cytoplasm • platelet alpha granule • cytosol • bilen • tertiary granule • Cellbilen • basolateral plasma membrane • specific granule • apical plasma membrane • extracellular exosome • phagocytic vesicle • presynapse Prosesau biolegol • protein to membrane docking • protein heterooligomerization • neutrophil degranulation • insulin secretion • vesicle docking involved in exocytosis • response to insulin • brain development • negative regulation of calcium ion-dependent exocytosis • protein transport • platelet aggregation • vesicle-mediated transport • exocytosis • GO:0015915 transport • cellular glucose homeostasis • negative regulation of glucose import • cellular response to interferon-gamma Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6814	n/a
Ensembl	ENSG00000116266	n/a
UniProt	O00186	n/a
RefSeq (mRNA)	NM_007269	n/a
RefSeq (protein)	NP_009200	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STXBP3 yw STXBP3 a elwir hefyd yn Syntaxin binding protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p13.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STXBP3.

• "Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells. ". Biochem J. 2014. PMID 25190515.
• "80K-H acts as a signaling bridge in intact living cells between PKCzeta and the GLUT4 translocation regulator Munc18c. ". J Recept Signal Transduct Res. 2008. PMID 19061073.
• "Munc18c in adipose tissue is downregulated in obesity and is associated with insulin. ". PLoS One. 2013. PMID 23700440.
• "Interaction of Munc18c and syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumor cells. ". J Biol Chem. 2017. PMID 28798239.
• "Protein expression of PKCZ (Protein Kinase C Zeta), Munc18c, and Syntaxin-4 in the insulin pathway in endometria of patients with polycystic ovary syndrome (PCOS).". Reprod Biol Endocrinol. 2012. PMID 22390153.