User:Gazirashid/sandbox: Difference between revisions

Content deleted Content added
No edit summary
Line 28:
* Cognitive impairments<ref name="Roth"/>
====Heritability====
There is a great deal of evidence to show that schizophrenia is a heritable disease. Twin studies have shown that the likelihood of developing the disease is 53% for one member of monozygotic twins (twins with same genetic code), compared to the 15% for dizygotic twins, who don't share the exact DNA <ref name="Sham"> Sham, P. Genetic Epidemiology, Br. Med. Bull. 52 (1996) 408-433. </ref>.
 
The fact that even monozygotic twins don't share a 100% [[concordance|concordance]] rate suggests environmental factors play a role in the vulnerability and development of the disorder. There are various environmental factors that have been suggested in various studies, including the use of marijuana, complications during pregnancy, socioeconomic status and environment, and maternal malnutrition. As the field of epigenetics advances, these and other external risk factors are likely to be considered in epidemiological studies <ref name="Roth"/>.
====Genetics====
Several genes have been identified as important in the study of schizophrenia, but there are a few that have special roles when studying the epigenetic modifications of the disease.