OGT may refer to:
- Ohio Graduation Test, a statewide exit test as a result of the No Child Left Behind Act
- Original Gangster Tool, someone who claims to have been a fan of rock/metal band Tool since the beginning (from the time of the release of the Opiate EP in 1992); term appears in Tool's 1996 song "Hooker with a Penis"
- OG: Original Gangster (Original Gangster Thug), a 1991 album by Ice-T
- Protein O-GlcNAc transferase, a human enzyme that catalyzes installation of the O-GlcNAc post-translational modification
- Ogt, O6-alkylguanine DNA alkyltransferase II, a protein also known as AGT II
This disambiguation page lists articles associated with the title OGT.
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