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Wikipedia:WikiProject Chemicals/Chembox validation/VerifiedDataSandbox and Trional: Difference between pages

(Difference between pages)
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Saving copy of the {{drugbox}} taken from revid 454809664 of page Trional for the Chem/Drugbox validation project (updated: 'CAS_number').
 
 
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{{short description|Chemical compound}}
{{ambox | text = This page contains a copy of the infobox ({{tl|drugbox}}) taken from revid [{{fullurl:Trional|oldid=454809664}} 454809664] of page [[Trional]] with values updated to verified values.}}
{{Infobox drug
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 447628315
| verifiedrevid =
| IUPAC_name = 2,2-bis(ethylsulfonyl)butane
| IUPAC_name = 2,2-bis(ethylsulfonyl)butane
| image = Trional_structure.png
| image = .
| width = 180
| width = 180
| image2 = Trional ball-and-stick.png
| width2 = 180


<!--Clinical data-->
<!--Clinical data-->
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<!--Identifiers-->
<!--Identifiers-->
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = <!-- blanked - oldvalue: 76-20-0 -->
| CAS_number = 76-20-0
| ATC_prefix = none
| ATC_prefix = none
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
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<!--Chemical data-->
<!--Chemical data-->
| C=8 | H=18 | O=4 | S=2
| C=8 | H=18 | O=4 | S=2
| molecular_weight = 242.356 g/mol
| smiles = CCC(C)(S(=O)(=O)CC)S(=O)(=O)CC
| smiles = CCC(C)(S(=O)(=O)CC)S(=O)(=O)CC
}}
}}

'''Trional''' ('''Methylsulfonal''') is a [[sedative-hypnotic]]<ref>{{cite book | date = 1907 | chapter-url = https://archive.org/stream/cu31924003469677#page/n465/mode/2up/ | chapter = Trional | title = Merck's 1907 Index | location = New York | publisher = Merck & Co. | page = 448 }}</ref> and [[anesthetic]] [[drug]] with [[GABAergic]] [[drug action|action]]s{{Citation needed|date=November 2010}}. It has similar effects to [[sulfonal]], except it is faster acting.<ref>{{cite journal | vauthors = Sajous CE | date = 1896 | title = General Therapeutics | url = https://archive.org/stream/1896annualofuniv05philuoft/#page/n169/mode/2up | journal = Annual of the Universal Medical Sciences | location = Philadelphia | publisher = F. A. Davis | volume = 5 | pages = A-156 }}</ref>

==History==
Trional was prepared and introduced by [[Eugen Baumann]] and [[Alfred Kast]] in 1888.<ref>{{cite book | vauthors = Drinkwater H | date = 1924 | url = https://archive.org/stream/fiftyyearsofmedi00drin#page/40/mode/2up | title = Fifty years of medical progress, 1873-1922 | location = New York | publisher = The Macmillan Company | page = 40 }}</ref>

== Cultural references ==

Appeared in Agatha Christie's ''[[Murder on the Orient Express]]'', ''[[And Then There Were None]]'', and other novels such as John Bude's ''[[The Lake District Murder]]'' as a sleep-inducing sedative; and in ''[[In Search of Lost Time]]'' (Sodom and Gomorrah) by [[Marcel Proust]] as a [[hypnotic]]. [[Sax Rohmer]] also references trional in his novel ''[[Dope (novel)|Dope]]''.

==See also==
* [[Sulfonal]]
* [[Tetronal]]

==References==
{{Reflist}}

{{Hypnotics}}
{{General anesthetics}}
{{GABAAR PAMs}}

[[Category:Hypnotics]]
[[Category:GABAA receptor positive allosteric modulators]]
[[Category:Sulfones]]


{{sedative-stub}}