Mojo unleashes a curse on Townsville that turns everyone into dogs, including the Powerpuff Girls! Luckily, they manage to sniff out a solution.
Vile villain Roach Coach has a plan to infest Townsville with an army of cockroaches! That is, until the Girls force him to bug off.
The Amoeba Boys' ill-conceived plan to stand in the rain all night leaves them with a nasty virus that's really something to sneeze at.
Buttercup falls for the leader of the Gangreen Gang. But when the gang exploits her infatuation, she shows them the real meaning of the word "crush.
The Boogie Man creates perpetual night by launching a huge disco ball to block out the sun. So the Powerpuff Girls plot to crash the ball.
The Gangreen Gang gets ahold of the Powerpuff Girls' Hotline and makes crank calls, sending the Powerpuff Girls on a wild goose chase all over town.
Major Man, a perfect new superhero in town, cuts in on the girls' turf. But the girls prove they're still integral to saving the day.
During a heat wave, Blossom discovers that she has a new power: ice breath. But when she doesn't use her new gift wisely, she gets a chilly reception.
Bubbles is tired of people dismissing her as more sugar than spice. So she sets out to take everyone by surprise -- even Mojo Jojo.
Fuzzy Lumpkins throws his hat into the mayoral ring and claims a surprise victory. So now it's up to the mayor and the girls to get him out of office.
The Powerpuff Girls lose their baseball in Mojo's house, giving him the perfect opportunity to destroy the pesky superheroines.
Mojo Jojo creates the ultimate weapons to use against the Powerpuff Girls: boy equivalents! Enter Butch, Boomer and Brick... the Rowdyruff Boys.
Worried about his little girls' safety, the Professor creates Powerpuff Dynamo, a state-of-the-art protection system, to help them in battle.
Bratty little Princess comes to town and wants to be a Powerpuff Girl. But when she doesn't get what she wants, the girls have to pay.
A fan of the Powerpuff Girls has collected every bit of Powerpuff stuff available. But his collection will be complete with just three more items.
It's the girls' birthday, and some presents have arrived from their main enemies. Can they destroy these evil gifts without destroying their party?
The Sandman would like a little rest, so he puts the world to sleep. But the girls must battle him in his dreams to get things back to normal.
When Broccoli Aliens from space invade Townsville, it's up to the Powerpuff Girls and all the children of Townsville to take a bite out of crime.
The girls save Big Billy's life, and he's forever indebted. But how will they get this bumbling fellow out of their way so they can save the world?
The girls are exhausted at school from saving Townsville past their bedtime. What will happen to their town when the girls are put on a curfew?
Princess hires Mojo to devise a plan to destroy the girls, who are shocked when they find that Princess has powers equal to their own.
Mojo observes that everyone is avoiding little Harry Pitt because he has "cooties." So he concocts a plan, using this cootie-covered boy as bait.
It's raining, and there's no crime or villainy afoot. So the girls must stay inside and come up with their own Powerpuff adventure.
The girls decide they need some help fighting crime, so they create another Powerpuff Girl. But there's something's a little off about her.
When the children of Pokey Oaks become envious of the Powerpuff Girls' superpowers, a mysterious figure offers them Chemical X.
When the girls decide to have an all-girl slumber party, a villain in a not-so-clever disguise decides to crash the fun.
When a gang of old-time villains comes out of retirement, the girls enlist the best superhero team of the past to save the city.
Mojo is unwittingly drafted to babysit the girls. Little does he know, taking care of them can be a big hassle.
The Professor's plans go awry when he tries to switch apples for oranges, causing the entire town to switch from one body to another.
Bubbles' fighting has been really terrible lately, and the Professor discovers that she needs glasses. Oh, the humanity.
A lazy Townsville cop gets fired and blames the Powerpuff Girls for saving the day too often and stealing his job. Now it's payback time.
A crook hides a huge diamond in a box of the Powerpuff Girls' favorite cereal. But how can he trick the girls into giving it back?
The Powerpuff Girls think they're experiencing deja vu when Mojo decides to reenact his "brilliant" plan step-by-step.
When the mayor gives the Powerpuff Girls some candy in gratitude for saving the day, they become hooked -- and that ain't good.
When the mayor realizes that the girls are doing all his work for him, he mans a hot-air balloon to fight crime the old-fashioned way.
The Powerpuff Girls are so busy fighting crime that the Professor doesn't get to see them anymore. So he creates a superhero suit and joins them.
Mojo, Him, Princess and Fuzzy band together to form the Bad Four, a criminal supergroup out to destroy the Powerpuff Girls.
A villain is sucking information from the brains of powerful people and committing crimes. Can the girls stop him before it's too late?
The girls leap into action when the Gangreen Gang shoplifts from a mini-mart, shoveling loads of food down their throats as fast as possible.
A sleazy film director shows up in town and wants to do a movie about the girls.
Him tricks Bubbles into bringing to life her chalk drawings, which then wreak havoc on Townsville. Talk about a tortured artist!
Mojo goes back in time to stop the Professor creating the "perfect little girl." But he ends up giving the young Professor just the spark he needs.
The girls must solve a series of complicated riddles by Him in order to keep the Professor from having to "pay."
When the girls try to join the all-male superhero organization, they learn that sometimes supermen aren't so super: They're misogynists.
When the Professor's college roommate sees his brilliant creations, he decides to cash in on the popularity of the Powerpuffs.
The new girl next door learns it's hard to be best friends with superheroes and soon starts hanging out with the wrong kind of kid: Princess!
Microscopic robots are raining terror on Townsville and the girls must fight with these creatures on their own tiny level.
In order to save an innocent squirrel, Bubbles gives him a dash of Chemical X, giving him some super squirrel powers.
A terrible, evil menace from outer space descends upon Townsville and the girls must turn to another evil menace in order to fight it: Mojo Jojo.
The girls set up Ms. Keane and the Professor on a date. / Blossom loses her confidence -- and her intelligence.
The girls have become paralyzed by their greatest fears. Who could be behind such an evil trick?
Buttercup goes on a quest to discover her superpower and her super self. / Bubbles gives a bunch of people their "happy" back.
Mayhem ensues when the monsters are forced to relocate to Townsville; Talking Dog hides out with the girls after witnessing a crime.
The mayor's craving for toast leads to a rampage that could destroy Townsville; the girls must fight multiple copies of the Amoeba Boys.
The girls try to stop a burglar without waking the exhausted professor; the professor's attempt to determine Fuzzy's species makes Fuzzy fall in love.
Mojo gets unlikely help in his crime spree from an animal rights group; the girls believe their new substitute teacher is a monster.
When Him resurrects the Rowdyruff Boys, the Powerpuff girls discover that their previous defense, kissing, now makes the boys bigger and stronger.
An evil gnome grants the girls' wish for peace in exchange for their powers in this musical parody episode
None of the girls wants to own up when they awaken to a wet bed; Princess Morbucks joins the PowerPuff Girls' fight against the Rowdyruff Boys.
A frozen caveman defrosts and goes on a rampage for seeds, which were his currency; clips recall the highlights of the series' first four seasons.
The girls learn the consequences of little white lies; Bubbles gets in over her head when she goes undercover with the Rowdyruff Boys.
A filmmaker has trouble getting good shots of the girls for a documentary; an anti-PowerPuff group learns the hard way how much the girls are needed.
Use of the wrong word leads a rampaging potty mouth to descend on Townsville; the girls compete with the Ganggreen Gang to raise funds for a laser.
The professor is taken prisoner in a silent movie; Townsville is besieged by animals who get away with burglary because they're just so cute.
One of Mojo's monkeys returns on a mission to do more evil; the Professor tricks out his car, only to have it turn possessive.
A fortune cookie sends Buttercup on a quest for inner peace; the girls bring home a hairy beast, mistaking him for the Professor's brother.
The Professor adds Chemical X to his entry for the chili cook-off with explosive results; the girls must uncover who turned D.Y.N.A.M.O against them.
Mojo's efforts to teach English bring Townsville to a halt; the Professor imagines what Townsville would be like if he'd made "normal" girls instead.
Evil Mask Scara defaces all the posters, statues and inhabitants of Townsville with permanent makeup. Can Blossom stop this makeover takeover?
The girls are convinced that the Professor wants to replace them; to stop the Mayor's recurring nightmare, the girls must enter his dreams.
Mojo and HIM argue over who is the evilest influence on the Rowdyruff Boys; Bubbles loses her voice just as mad squirrels attack Townsville.
The girls work to unmask the members of the Gangreen Gang and the mysterious disappearance of three Egyptian artifacts before Townsville is destroyed.
The girls rescue a baby but can't find its mother, so they must take care of it themselves; Mojo takes over the Narrator's job.
Suffering with terrible sunburns, the girls are too sore to fight crime; when a scientist turns Townsville gloomy, the girls must stop the crying.
After Mojo the Kid robs the first bank in the Old West and runs the sheriff out of town, the Professor creates the Steamypuff Girls to defeat him.
The girls literally work as one to stop Mojo from destroying Townsville; the girls must send a super-charged pirate crew back to the past.
Fuzzy and his nephews disrupt the girls' camping trip with the Professor; when Mojo turns the girls into giants, the Professor must find a solution.
The girls try to nab a phony psychic who stole a key from the mayor; Bubbles attempts to discover who assaulted Octi at her own party.