Zinc transporter 7

SLC30A7
Identifiers
Aliases	SLC30A7, ZNT7, ZnT-7, ZnTL2, solute carrier family 30 member 7
External IDs	OMIM: 611149; MGI: 1913750; HomoloGene: 11332; GeneCards: SLC30A7; OMA:SLC30A7 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	100,981,757 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	115,801,055 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; buccal mucosa cell; ; cartilage tissue; ; mucosa of paranasal sinus; ; tibia; ; visceral pleura; ; nasal epithelium; ; mucosa of ileum; ; jejunal mucosa; ; thymus;
	Top expressed in
	lacrimal gland; ; seminal vesicula; ; ectoderm; ; otic vesicle; ; saccule; ; Paneth cell; ; otic placode; ; medullary collecting duct; ; salivary gland; ; submandibular gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	cation transmembrane transporter activity; zinc ion transmembrane transporter activity;
Cellular component	cytoplasm; integral component of membrane; perinuclear region of cytoplasm; vesicle; Golgi apparatus; membrane; cytoplasmic vesicle;
Biological process	sequestering of zinc ion; regulation of sequestering of zinc ion; response to zinc ion; cation transport; zinc ion transport; ion transport; cation transmembrane transport; zinc ion transmembrane transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	148867
	66500
	ENSG00000162695
	ENSMUSG00000054414
	Q8NEW0
	Q9JKN1
	NM_001144884; NM_133496
	NM_023214
	NP_001138356; NP_598003
	NP_075703
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc transporter 7 is a protein that in humans is encoded by the SLC30A7 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000162695 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000054414 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kirschke CP, Huang L (Feb 2003). "ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus". J Biol Chem. 278 (6): 4096–102. doi:10.1074/jbc.M207644200. PMID 12446736.
^ "Entrez Gene: SLC30A7 solute carrier family 30 (zinc transporter), member 7".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Devergnas S, Chimienti F, Naud N, et al. (2004). "Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study". Biochem. Pharmacol. 68 (4): 699–709. doi:10.1016/j.bcp.2004.05.024. PMID 15276077.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000162695 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000054414 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12446736-5] Kirschke CP, Huang L (Feb 2003). "ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus". J Biol Chem. 278 (6): 4096–102. doi:10.1074/jbc.M207644200. PMID 12446736.

[entrez-6] "Entrez Gene: SLC30A7 solute carrier family 30 (zinc transporter), member 7".

[1]

Zinc transporter 7

See also

References

Further reading