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MAML3

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MAML3
Identifikatori
AliasiMAML3
Vanjski ID-jeviOMIM: 608991 MGI: 2389461 HomoloGene: 41284 GeneCards: MAML3
Lokacija gena (čovjek)
Hromosom 4 (čovjek)
Hrom.Hromosom 4 (čovjek)[1]
Hromosom 4 (čovjek)
Genomska lokacija za MAML3
Genomska lokacija za MAML3
Bend4q31.1Početak139,716,753 bp[1]
Kraj140,154,184 bp[1]
Lokacija gena (miš)
Hromosom 3 (miš)
Hrom.Hromosom 3 (miš)[2]
Hromosom 3 (miš)
Genomska lokacija za MAML3
Genomska lokacija za MAML3
Bend3|3 CPočetak51,593,328 bp[2]
Kraj52,012,497 bp[2]
Ontologija gena
Molekularna funkcija GO:0001105 transcription coactivator activity
Ćelijska komponenta jedro
nukleoplazma
nuclear speck
Biološki proces Notch signaling pathway
transcription initiation from RNA polymerase II promoter
GO:0009373 regulation of transcription, DNA-templated
transcription, DNA-templated
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
positive regulation of transcription of Notch receptor target
positive regulation of Notch signaling pathway
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_018717

NM_001004176

RefSeq (bjelančevina)

NP_061187

n/a

Lokacija (UCSC)Chr 4: 139.72 – 140.15 MbChr 3: 51.59 – 52.01 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Upravljački protein 3 (Drosophila) je protein koji je kod ljudi kodiran genom MAML3 sa hromosoma 4.[5]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 1.138 aminokiselina, a molekulska težina 122.293 Da.[6]

1020304050
MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPA
AGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQV
EQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQR
NHTLIMLQETVKRKLEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGM
EAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLP
EIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFS
DINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPL
SQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVAST
PAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGS
ASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQ
QQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQ
NPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYG
NTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQ
PPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL
PRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQL
IEQQKQQFLREQRQQQQQQQQQILAEQQLQQSHLPRQHLQPQRNPYPVQQ
VNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNPGTMATA
AAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGP
RQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQ
SLMGTVQQGAQSWQQRSLQGMPGRTSGELGPFNNGASYPLQAGQPRLTKQ
HFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARPMVMSG
LSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYERNAPQDVSYNYSGDG
AGGSFPGLPDGADLVDSIIKGGPGDEWMQELDELFGNP

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196782 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061143 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Mastermind-like 3 (Drosophila)".
  6. ^ "UniProt, Q96JK9" (jezik: engleski). Pristupljeno 29. 10. 2021.

Dopunska literatura

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