Princess Charlotte of Wales may refer to:
- Princess Charlotte of Wales (1796–1817) (Charlotte Augusta), the only child of George, Prince of Wales, later King George IV of the United Kingdom
- Princess Charlotte of Wales (ship), an East Indiaman launched in 1812 and broken up in 1831
- Princess Charlotte of Wales (born 2015) (Charlotte Elizabeth Diana), the second child and only daughter of William, Prince of Wales