Balofloxacin

Balofloxacin

Clinical data
ATC code	none
Identifiers
IUPAC name 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylaminopiperidin-1-yl)-4-oxoquinoline-3-carboxylic acid
CAS Number	127294-70-6 N
PubChem CID	65958
ChemSpider	59361 Y
UNII	Q022B63JPM
ChEMBL	ChEMBL1210954 Y
CompTox Dashboard (EPA)	DTXSID5046695
Chemical and physical data
Formula	C20H24FN3O4
Molar mass	389.427 g·mol−1
3D model (JSmol)	Interactive image
SMILES CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
InChI InChI=1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27) Y Key:MGQLHRYJBWGORO-UHFFFAOYSA-N Y
NY (what is this?)  (verify)

Balofloxacin (INN) is a fluoroquinolone antibiotic. It is sold under the brand name Q-Roxin in Korea, and under various names in India.^[1] It is not approved by the FDA for use in the United States.

Balofloxacin is a fluoroquinolone that has a broad spectrum in vitro activity against a wide range of Gram-positive and Gram-negative bacteria, with enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae.^[2] It functions by inhibiting the action of DNA-gyrase, preventing bacterial cells from reproducing or repairing themselves, resulting in cellular death.^[3]

Vomiting, headache, dizziness, stomach pain, nausea, diarrhea and decreased liver function are the most common side effects. In rare cases, Balofloxacin can lead to or worsen tendinitis,^[3] and muscular damage.^[3]

• Quinolones

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