 If you liked
Azumanga Daiou The Animation
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 ...then you might like
Sayonara Zetsubou Sensei
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Azumanga Daioh and Sayonara Zetsubou Sensei focus on the interaction between crazy teachers and zany students. Both are rather random and do not adhere to a strict plot, relaying on continous gags instead of storytelling. Azumanga Daioh is less insane, though, and its parodies can be enjoyed by all ages while Sayonara Zetsubou Sensei offers a kind of dark humour and a stock full of pop culture references that are aimed at an older audience.
doesn't have a real plot, only random stories put together. funny at times. is a give or take anime. similarity: 2*
they both feature an array of female students with unique personalities
the characters of azumanga daioh are a bit more realistic
those of zetsubou sensei are somewhat extreme
Both have a rather random plot line with humor catered towards those that enjoy insanity.