Revenge is what is in store for MacGyver when a master-of-disguise hit man, who MacGyver thought long dead, shows up. This causes MacGyver to flashback to their first encounter.
MacGyver takes a group of Phoenix Foundation employees for a recreational trip into the wilderness but learns that someone of the group might be an escaped criminal.
MacGyver and his grandfather have plans to go to a hockey game. However, when they stop by the Phoenix Foundation to get the tickets, they discover terrorists attempting to blow up a bomb.
Murdoc enlists MacGyver's help to rescue his sister from his former employer. She is scheduled to be executed during a Halloween Party put on by the professional assassination organization.
A cruise ship is the target of a terrorist attack and has three bombs hidden aboard. MacGyver and a friend from the agency are asked to dismantle the bombs before it's too late for the crew and passengers.
An old mentor of MacGyver's asks him to judge a physics competition. The mentor's son becomes despondent after failing to win the competition and locks himself in the lab with a homemade bomb.
When MacGyver's research into the wildlife around the planned building site of a marina threatens to cause a shutdown of the project, the owner hires a beautiful woman to persuade MacGyver to change his mind... by any means necessary.