Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle (Q24563216)

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31 December 2019

title

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle (English)

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31 December 2019

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GOA release 2020-03-11

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31 December 2019

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31 December 2019

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31 December 2019

author name string

Evangelos Papagrigoriou

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31 December 2019

Igor L Barsukov

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31 December 2019

Neil Bate

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31 December 2019

Ian J Fillingham

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31 December 2019

Bipin Patel

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31 December 2019

Ronald Frank

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31 December 2019

David R Critchley

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31 December 2019

Jonas Emsley

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31 December 2019

language of work or name

English

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publication date

22 July 2004

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31 December 2019

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volume

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issue

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page(s)

2942-2951

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Structural basis for amplifying vinculin activation by talin

31 December 2019

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Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

24 March 2017

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24 March 2017

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Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

24 March 2017

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24 March 2017

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Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

24 March 2017

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24 March 2017

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Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

24 March 2017

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A fluorescence cell biology approach to map the second integrin-binding site of talin to a 130-amino acid sequence within the rod domain

7 April 2017

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27 September 2017

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Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Further characterization of the interaction between the cytoskeletal proteins talin and vinculin.

30 May 2018

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Disruption of the talin gene compromises focal adhesion assembly in undifferentiated but not differentiated embryonic stem cells

30 May 2018

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Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

30 May 2018

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Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain

30 May 2018

1 reference

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Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans

21 January 2018

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Crosstalk between cell adhesion molecules: vinculin as a paradigm for regulation by conformation

21 January 2018

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

21 January 2018

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Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains.

21 January 2018

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Analysis of Repeated Motifs in the Talin Rod

21 January 2018

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Identification of functional domains in the cytoskeletal protein talin

21 January 2018

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12 December 2020

Microinjection of antibodies against talin inhibits the spreading and migration of fibroblasts

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12 December 2020

SPOT synthesis. Epitope analysis with arrays of synthetic peptides prepared on cellulose membranes

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12 December 2020

Down regulation of talin alters cell adhesion and the processing of the alpha 5 beta 1 integrin

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600285

2 references

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31 December 2019

1 reference

2 references

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31 December 2019

PubMed publication ID

15272303

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15272303%20AND%20SRC:MED&resulttype=core&format=json